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collagen type i alpha 1 chain  (Cell Signaling Technology Inc)


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    Structured Review

    Cell Signaling Technology Inc collagen type i alpha 1 chain
    Collagen Type I Alpha 1 Chain, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/collagen+type+i+alpha+1+chain/pmc12907279-90-12-44
    Average 86 stars, based on 1 article reviews
    collagen type i alpha 1 chain - by Bioz Stars, 2026-10
    86/100 stars

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    Related Articles

    other:

    Article Title: Inhaled Yiqi Huatan Sanjie formula and its component quercetin ameliorate pulmonary fibrosis by targeting core transcription factor JUN
    Article Snippet: #These authors contributed equally to this work and are co-first authors for this paper.. *Correspondence to: Han-Jiao Liu, Nursing Department, Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine, No. 3, Shajing Street, Shenzhen 518027, China.. E-mail: liuhanjiao75@gzucm.edu.cn.

    Control:

    Article Title: IFN-γ and TNF-α Impair Lung Development by Upregulating SMAD7 to Inhibit TGF-β Signaling Pathway and ECM Dysregulation
    Article Snippet: .. Primary antibodies were used as follows: α-smooth muscle actin (α-SMA, Cat#19245, 1:1000), collagen type I alpha 1 chain (COL1A1, Cat#91144, 1:1000), SMAD2 (Cat#5339, 1:1000), phosphorylated SMAD2 (p-SMAD2, Ser465/467, Cat#18338, 1:1000), SMAD3 (Cat#9523, 1:1000), phosphorylated SMAD3 (p-SMAD3, Ser423/425, Cat#9520, 1:1000), and SMAD4 (Cat#38454, 1:1000) from Cell Signaling Technology (CST, USA); SMAD7 (Cat#ab216428, 1:1000) from Abcam (UK); β-actin (1:1000) as loading control from Beijing Boaosen Biotechnology (Beigjing, China). .. Total RNA was extracted from cells/tissues with TRIzol reagent (Thermo Fisher Scientific) following the supplier’s instructions.

    Blocking Assay:

    Article Title: Lichong decoction improves inflammatory microenvironment and alleviates fibrosis in uterine leiomyoma via targeting CXCL8.
    Article Snippet: Ethnopharmacological relevance: Lichong decoction (LD) is extensively employed in the treatment of uterine leiomyoma (ULM), demonstrating remarkable clinical effectiveness with an absence of notable adverse reactions.. Its composition aligns with the traditional Chinese medicine (TCM) etiology of ULM, making it a highly suitable therapy.. Nonetheless, the precise mechanisms underlying its therapeutic actions remain to be fully elucidated.

    Incubation:

    Article Title: Lichong decoction improves inflammatory microenvironment and alleviates fibrosis in uterine leiomyoma via targeting CXCL8.
    Article Snippet: Ethnopharmacological relevance: Lichong decoction (LD) is extensively employed in the treatment of uterine leiomyoma (ULM), demonstrating remarkable clinical effectiveness with an absence of notable adverse reactions.. Its composition aligns with the traditional Chinese medicine (TCM) etiology of ULM, making it a highly suitable therapy.. Nonetheless, the precise mechanisms underlying its therapeutic actions remain to be fully elucidated.



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    The protective effects of rhein from dexamethasone (Dex)-osteoporosis mice on serum bone metabolism index. (A) The detailed schedule of animal experiments. (B) Body weight of mice in the initial group. (C) The change in the body weight of mice. (D–I) The bone metabolism index of serum levels, including alkaline phosphatase (ALP) (D), osteocalcin/bone gla protein (OT/BGT) (E), osteoprotegerin (OPG) (F), collagen type I <t>alpha</t> <t>1</t> chain <t>(COL1A1)</t> (G), calcium (Ca) (H), and phosphorus (I). n = 6, ### P < 0.001, ## P < 0.01 vs. Control; ∗∗∗ P < 0.001, ∗∗ P < 0.01, ∗ P < 0.05 vs. Dex. ns: not significant vs. Control. PTH: parathyroid hormone 1-34; R(L): rhein low-dose group; R(H): rhein high-dose group.
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    The protective effects of rhein from dexamethasone (Dex)-osteoporosis mice on serum bone metabolism index. (A) The detailed schedule of animal experiments. (B) Body weight of mice in the initial group. (C) The change in the body weight of mice. (D–I) The bone metabolism index of serum levels, including alkaline phosphatase (ALP) (D), osteocalcin/bone gla protein (OT/BGT) (E), osteoprotegerin (OPG) (F), collagen type I <t>alpha</t> <t>1</t> chain <t>(COL1A1)</t> (G), calcium (Ca) (H), and phosphorus (I). n = 6, ### P < 0.001, ## P < 0.01 vs. Control; ∗∗∗ P < 0.001, ∗∗ P < 0.01, ∗ P < 0.05 vs. Dex. ns: not significant vs. Control. PTH: parathyroid hormone 1-34; R(L): rhein low-dose group; R(H): rhein high-dose group.
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    The protective effects of rhein from dexamethasone (Dex)-osteoporosis mice on serum bone metabolism index. (A) The detailed schedule of animal experiments. (B) Body weight of mice in the initial group. (C) The change in the body weight of mice. (D–I) The bone metabolism index of serum levels, including alkaline phosphatase (ALP) (D), osteocalcin/bone gla protein (OT/BGT) (E), osteoprotegerin (OPG) (F), collagen type I <t>alpha</t> <t>1</t> chain <t>(COL1A1)</t> (G), calcium (Ca) (H), and phosphorus (I). n = 6, ### P < 0.001, ## P < 0.01 vs. Control; ∗∗∗ P < 0.001, ∗∗ P < 0.01, ∗ P < 0.05 vs. Dex. ns: not significant vs. Control. PTH: parathyroid hormone 1-34; R(L): rhein low-dose group; R(H): rhein high-dose group.
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    The protective effects of rhein from dexamethasone (Dex)-osteoporosis mice on serum bone metabolism index. (A) The detailed schedule of animal experiments. (B) Body weight of mice in the initial group. (C) The change in the body weight of mice. (D–I) The bone metabolism index of serum levels, including alkaline phosphatase (ALP) (D), osteocalcin/bone gla protein (OT/BGT) (E), osteoprotegerin (OPG) (F), collagen type I <t>alpha</t> <t>1</t> chain <t>(COL1A1)</t> (G), calcium (Ca) (H), and phosphorus (I). n = 6, ### P < 0.001, ## P < 0.01 vs. Control; ∗∗∗ P < 0.001, ∗∗ P < 0.01, ∗ P < 0.05 vs. Dex. ns: not significant vs. Control. PTH: parathyroid hormone 1-34; R(L): rhein low-dose group; R(H): rhein high-dose group.
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    Image Search Results


    The protective effects of rhein from dexamethasone (Dex)-osteoporosis mice on serum bone metabolism index. (A) The detailed schedule of animal experiments. (B) Body weight of mice in the initial group. (C) The change in the body weight of mice. (D–I) The bone metabolism index of serum levels, including alkaline phosphatase (ALP) (D), osteocalcin/bone gla protein (OT/BGT) (E), osteoprotegerin (OPG) (F), collagen type I alpha 1 chain (COL1A1) (G), calcium (Ca) (H), and phosphorus (I). n = 6, ### P < 0.001, ## P < 0.01 vs. Control; ∗∗∗ P < 0.001, ∗∗ P < 0.01, ∗ P < 0.05 vs. Dex. ns: not significant vs. Control. PTH: parathyroid hormone 1-34; R(L): rhein low-dose group; R(H): rhein high-dose group.

    Journal: Journal of Pharmaceutical Analysis

    Article Title: Discovery of anthraquinones as potent Notum inhibitors for treating osteoporosis by integrating biochemical, phytochemical, computational, and experimental assays

    doi: 10.1016/j.jpha.2025.101256

    Figure Lengend Snippet: The protective effects of rhein from dexamethasone (Dex)-osteoporosis mice on serum bone metabolism index. (A) The detailed schedule of animal experiments. (B) Body weight of mice in the initial group. (C) The change in the body weight of mice. (D–I) The bone metabolism index of serum levels, including alkaline phosphatase (ALP) (D), osteocalcin/bone gla protein (OT/BGT) (E), osteoprotegerin (OPG) (F), collagen type I alpha 1 chain (COL1A1) (G), calcium (Ca) (H), and phosphorus (I). n = 6, ### P < 0.001, ## P < 0.01 vs. Control; ∗∗∗ P < 0.001, ∗∗ P < 0.01, ∗ P < 0.05 vs. Dex. ns: not significant vs. Control. PTH: parathyroid hormone 1-34; R(L): rhein low-dose group; R(H): rhein high-dose group.

    Article Snippet: The levels of bone metabolism index in mouse serum, including alkaline phosphatase (ALP), osteocalcin/bone gla protein (OT/BGT), osteoprotegerin (OPG), and collagen type I alpha 1 chain (Col1A1), were measured using commercial enzyme-linked immunosorbent assay (ELISA) kits (ABclonal Biotechnology Co., Ltd., Wuhan, China).

    Techniques: Control